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Testosterone Replacement Therapy (TRT) is a form of hormone therapy in which androgens, often testosterone, are replaced. It is a widely used treatment for men with symptomatic hypogonadism.



Testosterone is a hormone essential to the development of male growth and masculine characteristics. It plays a key role in muscle mass, bones, facial and public hair, vocal cords, sex drive, mood, quality of life, verbal memory and thinking ability.

Those with low Testosterone generally have these symptoms:

  • Low sex drive

  • Erectile dysfunction

  • Fatigue and poor energy level

  • Decreased muscle mass

  • Body and facial hair loss

  • Difficulty concentrating

  • Depression

  • Irritability

  • Low sense of well-being


  • Less fat and more muscle

  • Stronger bone density and protection against osteoporosis

  • Increased mental sharpness and spacial abilities

  • Improved mood and sense of well-being

  • Improved sexual function

  • Healthier heart

  • Greater muscle strength and physical performance


  1. WebMD Staff. Is Testosterone Replacement Therapy Right for You? WebMD.com.

  2. Written by Ann Pietrangelo medically reviewed by Graham Rogers, MD. (2016 November 30). How Testosterone Benefits Your Body. Healthline.com.

  3. The Endocrine Society. Testosterone Therapy in Men Accessed 4/13/2018.

  4. American Urological Association. What is Low Testosterone? Accessed 4/13/2018.

  5. Bhasin S et al. J Clin Endocrinol Metab, May 2018, 103(5):1–30.

  6. Pantalone KM, Faiman C. Male hypogonadism: More than just a low testosterone. Cleveland Clinic Journal of Medicine, Volume 79, Number 10, 717-725.