Benefits of NAD+ IV Therapy: A Complete Guide

• August 3, 2023
• Written by :  Rebecca LaMarca, MSN, APN-BC, CNS

Imagine waking up with steady energy, sharper focus, and faster workout recovery. That’s the dream driving many people toward NAD+ infusions. NAD+ is a coenzyme involved in essential functions like energy production, cellular health, and DNA repair. As you get older, your NAD+ levels fall. But you can restore them with NAD+ IV therapy, an infusion treatment that delivers the coenzyme right to your bloodstream. As the therapy becomes more popular, studies have found that it may be linked to a number of health benefits. Here’s what you should know about the benefits of NAD IV therapy and how you can experience them in New Jersey, New York City, and Philadelphia.  

    NAD+ levels decline steadily with age, dropping approximately 50% by age 50 and continuing to fall through later decades. Restoring NAD+ through IV therapy is one approach studied for supporting cellular function during this decline. Sources: Massudi et al. (2012); Camacho-Pereira et al. (2016); Lautrup et al. (2019).

What are all the benefits of NAD therapy?

Researchers are actively studying NAD+ IV therapy benefits every day. So far, these are the benefits with the most scientific support:

Increased energy

NAD+ plays a key role in your body’s energy production. Specifically, it helps your body turn nutrients from food into electron carriers that support the production of adenosine triphosphate (ATP). ATP is your body’s main energy source.

By restoring your NAD+ levels, you may experience an energy burst that makes it easier to get through your day. Research suggests that NAD+ therapy may also help you beat symptoms of fatigue, including whole body tiredness, brain fog, and loss of interest in activities.

Reduced signs of aging

Everyone wants to age as gracefully as possible, especially when it comes to their skin. Studies suggest that NAD+ may support your skin’s natural repair systems, helping cells mend damage from UV exposure, oxidative stress, and other environmental stressors. Your skin gets more vulnerable to this damage as you get older and your NAD+ levels drop. This can lead to signs of aging such as:

• wrinkles
• fine lines
• dullness
• thinness
• slow wound healing

By helping your skin protect itself, NAD+ infusions could potentially decrease these signs and restore your confidence in your skin.

Also, because it supports DNA repair in brain cells, NAD+ might help reduce age-related issues with memory, focus, and mental clarity. It may also ease problems with energy, metabolism, and muscle function. These benefits might be linked to how NAD+ supports the activation of sirtuins, a group of proteins associated with aging and inflammation.

Better brain health

NAD+ may help keep your brain healthy by supporting brain cell repair and reducing oxidative stress, which can damage your brain cells over time. In fact, NAD+ deficiencies have been linked to neurocognitive disorders like Alzheimer’s disease and Parkinson’s disease.

While research is ongoing, brain-related benefits of NAD+ therapy may include:

• improved focus and concentration
• increased cognitive functioning
• better memory
• better mood
• reduced anxiety and depression

Some studies even suggest that NAD+ IV therapy may help ease withdrawal symptoms and cravings caused by substance use disorder (addiction).

Healthier sleep

Your NAD+ levels are involved in your circadian rhythm and clock-gene regulation. That’s why some researchers think boosting NAD+ levels may have an impact on your sleep quality. Although more studies are needed, some people who get NAD IV therapy have reported sleep-related benefits like:

• falling asleep faster
• experiencing deeper sleep
• feeling more refreshed upon waking

These benefits can have a big impact on your ability to meet your daily goals.

Less inflammation

Chronic inflammation often stems from oxidative stress and impaired cellular energy metabolism. Because NAD+ can help manage both of these problems, NAD+ IV therapy might help reduce inflammation over time. This benefit could make you less likely to get chronic diseases, especially as you age. Also, since chronic inflammation is linked to insulin resistance, NAD+ IV therapy might help improve blood sugar control and reduce your risk of metabolic disorders. It may also help you manage pain or mobility issues.

Improved metabolism

NAD+ helps your body make energy by driving metabolic processes like glycolysis, the Krebs cycle, and mitochondrial ATP production. Also, because it influences cellular repair, NAD+ might help your cells maintain normal metabolic function when stressed. That’s why some researchers think that NAD+ IV therapy could support your metabolism. This benefit could help you feel energized throughout the day and stay at a healthy weight.

Easier athletic recovery

NAD+ IV therapy’s positive effects on energy metabolism and cellular repair could support athletic recovery, helping you stay active more often. You might notice your energy levels stay higher throughout a training session. In addition, you may find it easier to recover from fatigue and injuries following especially intense sessions. That means you can get back to your activities faster, making it easier to meet your health goals.

Who can benefit most from NAD+ IV therapy?

Anyone interested in the effects listed above could benefit from NAD+ IV therapy. But you might find it especially helpful if you struggle with fatigue, high stress, sleep troubles, recovery demands, or age-related energy problems. Some studies also suggest that the treatment may be particularly beneficial for people with certain health conditions, including chronic fatigue syndrome, substance use disorder (addiction), Alzheimer’s disease, and Parkinson’s disease.

If you’re ready to start your NAD+ IV journey, reach out to the certified team at IV Elements. Our drip lounges in South and North Jersey offer the perfect calming environment to restore your NAD+ levels. You can also experience NAD IV benefits in NYC and Philadelphia by booking an in-home session through our mobile service!

But before you can enjoy in-lounge or in-home NAD IV therapy benefits, you should always talk to a healthcare professional. They can help you figure out whether the infusions are right for you based on your goals and health. For example, you should not get NAD therapy if you:

• are pregnant or breastfeeding
• have a known allergy to NAD
• have severe liver or kidney disease

Elevate your wellness journey with NAD+ IV therapy from IV Elements

The board-certified nurses at IV Elements are eager to help you experience NAD IV therapy benefits in New Jersey, New York City, and Philadelphia. Alongside leading scientists and physicians, we explored the latest research on NAD therapy benefits at the Springfield Wellness Center 2020 NAD+ Brain Restoration Summit, and we’re committed to bringing those benefits to you.

We offer fully customizable drips at our lounges in Hoboken, Asbury Park, Parsippany, and Marlton. Prefer to stay home? Book our convenient mobile NAD therapy across NJ, NYC, Philadelphia, and Bucks County! As proud members of the Physicians’ Association for Anthroposophic Medicine (PAAM) and Institute of Functional Medicine (IFM), we specialize in personalized, integrative care to help you feel your best. Schedule your first session today!

Frequently Asked Questions

Where in New Jersey can I experience NAD IV therapy benefits?

The certified nurses at IV Elements offer NAD+ IV therapy at our drip lounges in Hoboken, Asbury Park, Parsippany, and Marlton, NJ. You can also experience the benefits of mobile NAD IV therapy in NJ by booking an in-home infusion! Our mobile nurses serve NJ, NYC, Philadelphia, and Bucks County, PA.

Does NAD therapy increase energy?

Studies suggest that NAD therapy might boost energy because NAD helps your body make energy from food. Many people who get the infusions say they feel less tired and that it’s easier to get through their day.

Does NAD therapy improve cognitive function?

It might, especially since NAD+ can reduce oxidative stress, which may damage your brain cells over time. NAD+ can also help your brain cells fix themselves after getting damaged. That may be why some people who get NAD+ infusions say it’s easier to focus and remember things.

Does NAD therapy slow aging?

Some researchers think NAD therapy could slow signs of aging such as poor memory, low energy, and skin changes like wrinkles and fine lines. That’s because NAD+ plays an important role in aging-related functions like energy production, DNA repair, and stress responses.

Does NAD therapy help athletic recovery?

Since NAD+ helps your body metabolize energy and repair cell damage, it may indeed make athletic recovery easier. Some people say that the infusions help them feel more energized, less fatigued, and more able to bounce back after an intense training session.

Does NAD therapy improve sleep?

NAD+ levels have been linked to your sleep-wake cycle. After getting NAD+ IV therapy, some people report that they have an easier time falling and staying asleep, and others also report feeling more well-rested during the day.

Does NAD therapy support mood?

Because NAD+ may support brain cell health, some researchers think NAD+ IV therapy might help you maintain a calmer, happier mood. It could also help with mental health problems like anxiety, depression, and brain fog.

References

1. Blomquist, S. A., Kelly, G., Adães, S., Ardagh, A., Ramer, S., & Scuba, W. (2025, January 1). Qualia NAD+ increases NAD+, improves well-being, and alleviates aging symptoms: A randomized, double-blind, placebo-controlled study. medRxiv. https://www.medrxiv.org/content/10.1101/2025.05.14.25327611v1.full
2. Gallagher, C., & Emmanuel, O. O. (2026). NAD+ supplementation for anti-aging and wellness: A PRISMA-guided systematic review of preclinical and clinical evidence. Ageing Research Reviews, 116, 103057. https://doi.org/10.1016/j.arr.2026.103057
3. Lautrup, S., Sinclair, D. A., Mattson, M. P., & Fang, E. F. (2019). NAD+ in brain aging and neurodegenerative disorders. Cell Metabolism, 30(4), 630–655. https://doi.org/10.1016/j.cmet.2019.09.001
4. Massudi, H., Grant, R., Braidy, N., Guest, J., Farnsworth, B., & Guillemin, G. J. (2012). Age-associated changes in oxidative stress and NAD+ metabolism in human tissue. PLoS ONE, 7(7), e42357. https://doi.org/10.1371/journal.pone.0042357
5. Camacho-Pereira, J., Tarragó, M. G., Chini, C. C. S., Nin, V., Escande, C., Warner, G. M., Puranik, A. S., Schoon, R. A., Reid, J. M., Galina, A., & Chini, E. N. (2016). CD38 dictates age-related NAD decline and mitochondrial dysfunction through an SIRT3-dependent mechanism. Cell Metabolism, 23(6), 1127–1139. https://doi.org/10.1016/j.cmet.2016.05.006
6. NAD Research, Inc. (2023, December 2). IV NAD evaluating and refining assessment of withdrawal symptoms associated with opioid and alcohol use disorders. https://nadresearch.org/ivnad-withdrawal-symptom-assessment/

• Share
• Tweet
• Share
• Email